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Late-Night Drinking ['kɔfi]['lʌvəs] [bi'wεə]['hæviŋ][kwik][pik]['kɔfi][leit] [leit][nait] Coffee lovers beware.Having a quick “ pick-me-up” cup of coffee late inthe day will play havoc with your sleep.As well as being a stimulant, caffeine[,intə'rʌpts][fləu][,melə'təunin][brein]['hɔ:məun][ðæt] [send ]['pi:pl] [dei][plei] ['hævək][jɔ:][sli:p][wel]['bi:ŋ]['stimjulənt]['kæfi:n] interrupts the flow of melatonin, the brain hormone that sends people into a sleep.[sli:p][,melə'təunin] ['levəls] ['nɔ:məli][stɑ:t][raiz][ə'baut]['auəs][bi'fɔ:]['bedtaim] Melatonin levels normally start to rise about two hours before bedtime.['levəl][ðen][pi:k][bi'twi:n][fɔ:l ][ə'ɡen]
[,njuərəu'hɔ:məun][kən'trəul]['auə]['bɔdi][hwen] Levels then peak between 2 a.m.and 4 a.m , before falling again.“It’s theneurohormone that controls our sleep and tells our body when to sleep and[weik][sez]when to wake,” says Maurice Ohayon of the Stanford Sleep Epidemiklogy
[ri'sə:tʃ]['sentə][,ju:ni'və:səti]加利福尼亚以色列
[hæv][faund]['kæfiəneitid][hɑ:vz]['bɔdi]['levəl]Research Center at Stanford University in California.But researchers in Israelhave found that caffeinated coffee halves the body’s levels of this sleep hormone.['hɔ:məun][ti:m][sepe:] ['medikəl] ['sentə][,ju:ni'və:səti] Lotan Shilo and a team at the Sapir Medical Center in Tel Aviv University
[faund][siks] [,vɔlən'tiə][slept] [les][wel]['ɑ:ftə]['kæfiəneitid]['kɔfi]
['ɑ:ftə] ['driŋkiŋ][seim][ə'maunt]['di:,kæf]['ævəridʒ]['sʌbdʒikt][slept]found that six volunteers slept le well after a cup of caffeinated coffee thanafter drinking the same amount of decaf.On average, subjects slept 336
['minits][强pə:,]['kæfiəneitid][kəm'pεəd][wið]['minit]
['di:,kæf][ðei] ['ɔ:lsəu] [tuk][hɑ:f]['auə][drɔp][ɔ:f][twais][lɔŋ]
['ju:ʒuəl][dʒiɡ ][ə'raund][twais][mʌtʃ] minutes per night after drinking caffeinated coffee,compared with 415 minutesafter decaf.They also took half an hour to drop off---twice as long asusual---and jigged around in twice as much..['sekənd][feiz][ik'speriment][ri'sə:tʃ ][wəuk]In the second phase of the experiment, the researchers woke the
[,vɔlən'tiəs]['evri][θri:][ɑ:sk ][ɡiv]['juərin] ['sɑ:mpl]希洛
['meʒəd][,kɔnsən'treiʃən]['breikdaun]['prɔdəkt][,melə'təunin] volunteers every three hours and asked them to give a urine sample.Shilomeasured concentrations of a breakdown product of melatonin.The
[ri'zʌlt ][sə'dʒest][,melə'təunin][,melə'təunin ]['kæfi:n][wə:][hɑ:f] results suggest that melatonin concentrations in caffeine drinkers were half
[ðəuz]['di:,kæf]['peipə][ək'septid][强 fɔ:,][,pʌbli'keiʃən][sli:p]['medisin]those in decaf drinkers.In a paper accepted for publication in Sleep Medicine,[sə'dʒest]['kæfi:n][blɔk][prəu'dʌkʃən]['enzaim]
[draiv ][,melə'təunin][prəu'dʌkʃən] the researchers suggest that caffeine blocks production of the enzyme thatdrives melatonin production.[bi'kɔz][强kæn] [teik] ['meni]['auə ][i'limineit]['kæfi:n][强frɔm] ['bɔdi]欧哈永[,rekə'mend]['lʌvəs][switʃ]['di:,kæf] ['ɑ:ftə][lʌntʃ] Because it can take many hours to eliminate caffeine from the body,Ohayon recommends that coffee lovers switch to decaf after lunch.