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摘要题目(题目:Times New Roman, 三号字, 加粗, 居左)作者1 , 通讯作者2*(作者:Times New Roman, 小四号字, 加粗)部门1,单位1, 地址1,城市1,国家1;(单位地址:Tims New Roman, 五号字,斜体)2部门2, 单位2, 地址2, ,城市2, 国家2.Gallic acid metabolites represent a unique family of plant secondary metabolites present widely in the plant kingdom in the forms of polygalloyl esters of polyols, galloyl conjugates of catechins[1,2].They have many bioac-tivities such as anti-inflammatory[3], antimutegenesis [4,5], antiviral activities[6].摘要正文:Times New Roman, 小四号字, 单倍行距;其中,参考文献应用方括号和数字标注[1] and [2,3]

关键词: Gallic acid metabolites(Times New Roman, 小四号字)

致谢: This work was supported by....(Times New Roman, 小四号字, 单倍行距)参考文献:

[1]姓名, 姓名(年)文件名.杂志名, 卷期, 页码范围.(Times New Roman,小五号字, 单倍行距)

[2]A.B.Smith, C.D.Brown(Year)File name.Journal, Vol, Initial page.页面设置:A4纸张,距离上方 3 cm, 下方3 cm, 左方3 cm,右方3 cm

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*第一作者或通讯作者的E-mail:

Structure-Activity Relationships in the Bioactivities of Gallic Acid Metabolites and Their Interactions with Bioplymers Huiru Tang1*, Chaoni Xiao1 and Baolu Zhao2

1State Key Laboratory of Magnetic Resonance and Molecular and Atomic Physics, Wuhan Institute of Physics and Mathematics,The Chinese Academy of Sciences,Wuhan 430071 2State Key Laboratory of Brain and Recognition Laboratory, Institute of Biophysics, The Chinese Academy of Sciences, Beijing 100101, China

Gallic acid metabolites represent a unique family of plant secondary metabolites present widely in the plant kingdom in the forms of polygalloyl esters of polyols, galloyl conjugates of catechins[1,2].They have many bioactivities such as anti-inflammatory[3], antimutegenesis [4,5], antiviral activities[6].These metabolites readily bind with collagen and cellulose with hydrophobic interactions[8], and poe outstanding antioxidant and neuroprotective acitivites[9].Here, we will report the structure-activity relationships in the neuroprotective activities and the interactions with biopolymers for the GA metabolites.We will further discu some most recent results from our metabonomic investigation on the effects of gallic acid on the endogenous metabolism of rodent models.Keywords: Gallic acid metabolites

Acknowledgements: Financial supports from NSFC and the Chinese Academy of Sciences(20575074, 06S138)are acknowledged.Rererences:

[1]V.L.Singleton(1981), Adv.Food Res.27:149.[2] N.Niho, M.Shibutani et al(2001), Food Chem.Toxicol.39:1063.[3] B.H.Kroes, A.J.J.Vandenberg et al(1992), Plant.Med.58:499.[4] S.C.Chen, K.T.Chung(2000), Food Chem.Toxicol.38:1.[5] M.Kawada, Y.Ohno et al(2001), Anti-Cancer Drugs, 12:847.[6] H.X.Xu, S.Kadota et al(1994), Heterocycles 38:167.[7] H.R.Tang, A.D.Covington, R.A.Hancock(2003), Biopolymers, 70:403.[8] H.I.Oh, J.E.Hoff, G.S.Armstrong & L.A.Haff(1980), J.Agri.Food Chem.28:394.[9] Z.B.Lu, G.J.Nie, P.S.Belton, H.R.Tang & B.L.Zhao(2006), Neurochem.Int., 48:263.*E-mail:Huiru.tang@wipm.ac.cn

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